Neuroimmune signaling by extracellular vesicles

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Neuroimmune signaling by extracellular vesicles

Systemic inflammation has a strong impact on brain function and contributes to the immediate and long-term development of various pathologies. The classic view is that a systemic inflammation influences the brain via the release of inflammatory cytokines (e.g. IL-1ß, IL6, TNFα), which in turn activate microglia directly or via endothelial cells but may also act on neurons. As a neural mechanism...

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ژورنال

عنوان ژورنال: Oncotarget

سال: 2015

ISSN: 1949-2553

DOI: 10.18632/oncotarget.5249